Tuesday , June 28 2022

New study gives reason for hope for cancer therapy


  • New hope in the treatment of bowel cancer and pancreatic cancer
  • To be able Antidepressants slow tumor growth?
  • Antidepressants for cancer: First promise Tests with mice

New studies on cancer treatment give patients hope: According to Swiss researchers, the well-known antidepressant “Prozac” can prevent the growth of colon tumors and pancreatic cancer. This is evidenced at least by the first promising tests with mice.

Antidepressants for cancer: “Prozac” is said to slow tumor growth

In a current study, a team of researchers from the University of Zurich investigated how serotonin affects cancer cells. Serotonin is also known as the “happiness hormone” and is primarily responsible for our mood. People with low serotonin levels may suffer from depression. So many common antidepressants start here. They are often inhibitors of serotonin reuptake and increase the levels of serotonin in the brain.

However, most of the serotonin is produced in the lining of the intestine and stored in platelets. Serotonin reuptake inhibitors (SSRIs) increase the level of serotonin in the brain, thereby reducing the level of serotonin in the platelets. Cancer cells use the messenger substance serotonin to camouflage themselves from immune cells, as the researchers found.

How can the antidepressant “Fluoxetine”, better known as “Prozac”, help with cancer? Because antidepressants lower the levels of serotonin in the platelets, tumors can no longer use the messenger substance. In experiments with mice, the researchers found that tumor growth slowed significantly in mice and that more T cells in the cancerous tumors had migrated to fight the cancer.

Serotonin blockers help identify tumor cells

One researcher from the study states: “Antidepressants and other serotonin blockers cause the immune cells to recognize the tumor cells again and eliminate them efficiently.” The growth of colon and pancreatic cancer could be slowed in mice.

Book tip: Cancer cells do not like raspberries – look at Amazon

“Our results give hope to cancer patients because the drugs used are already approved for clinical use,” says researcher Pierre-Alain Clavien. Hopefully, clinical trials will also begin Antidepressants for cancer start soon.

Also interesting: Antibiotics increase risk of bowel cancer: study shows relationship

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