A steroid that is often used in inhalers for asthmatics can help prevent more serious symptoms of covida-19 in adults. According to research published in the scientific journal The Lancet, this widely used drug could prove effective in treating covida-19 at an early stage. The study was prompted by reports of a very low proportion of patients with chronic respiratory disease among hospital-covide patients.
Oxford University researchers found that patients who took the anti-asthmatic budesonide when they first developed covida-19 symptoms were less likely to have a more serious course of the disease that would otherwise require hospitalization or even intensive care. soe. The recovery time was shorter, and the chance of persistent symptoms and fever was lower, reports the German Deutsche Welle.
Reason for the study: low proportion of patients with chronic respiratory distress among hospital covid patients
The study was prompted by reports of a very low proportion of patients with chronic respiratory diseases among hospital covide patients. Therefore, they hypothesize that the reason for this is the widespread use of inhaled glucocorticoids – a type of corticosteroid – in these people.
Randomized trials included 146 adults within seven days of the onset of mild symptoms of covida-19. Half of them took budesonide twice a day until the symptoms disappeared, and the other half received normal care depending on their age, gender, and pre-existing conditions. In the first half only one person needed medical care, in the second half there were ten such people.
Due to the second anti-crown closure in the UK and other reasons, testing had to be terminated prematurely, but an independent statistical evaluation showed that the inclusion of subsequent participants was not expected to affect the outcome of the study itself. .
The findings could help reduce pressure on hospitals during a pandemic
As noted by one of the study’s authors, a professor of respiratory medicine at the University of Oxford Mona Bafadhel, their findings are particularly important because they can make a significant contribution to reducing pressure on hospitals during a pandemic. Budesonide is a widely available, affordable and relatively safe drug that could be prescribed by doctors in the early stages of covida-19.
According to experts, there is an important biological change that corticosteroids – including dexamethasone, which is already used in hospitals patients with covid-19, because it should inhibit inflammation associated with a more serious course of the disease – may actually help . Budesonide probably works as well, but often more localized.
Studies and laboratory tests have already shown that the use of inhaled steroids in people with asthma and chronic obstructive pulmonary disease inhibits the cellular receptor which allows SARS-CoV-2 to enter the lungs and possibly prevent the virus from multiplying, Deutsche Welle reports.