Researchers at MIT have developed a new type of sensor that could make diagnosis of sepsis much faster, easier and more affordable than ever before. This can have a huge potential impact, at least one of the leading causes of & # 39; A death is in hospitals, and is responsible for almost 250,000 patient days per year in FS only.
The method developed by MIT uses microfluidics to detect the presence of key proteins in the blood that act as early warning signs over the onset of sepsis. One in & # 39; special, called & # 39; interleukin-6 or IL-6, appears hours before another symptom appears in a patient. Normal & # 39; assay & # 39; as blood test devices, however, they cannot pick up as quickly as, despite the fact that it can spike early, these spikes do not represent significantly high levels relative to what these traditional methods are capable of.
My system can automatically register these higher concentrations early, with less blood than you would get yourself from a finger prick. Results are available in just 25 minutes, contrasting hours with traditional methods, as well as half an hour for more modern & # 39; point-of-care & # 39; Systems that have been brought to the market lately, however, can increase blood levels and are generally much more expensive.
The way MIT could work on these restrictions was by using a test method that reflects a lab-based detection method for IL-6 that uses small magnetic beads to show the presence of the protein, while decreases the size, so it is field-active. Existing field methods use high-quality optics, which are expensive and do not allow much in the way of cost-saving innovations, and keep the price of these tests and the hardware you need for them to limit for wide use.
Researchers plan to continue their work by developing a complete panel of proteins that act as early sepsis markers to enhance the accuracy of their diagnosis. The system could be tuned to detect a range of different biomarkers, however, so that its potential applications could also expand to other diagnostics.