Thursday, November 22, 2018 – 12:55 Update: 24-11-2012 18:28
Previous studies have already indicated that patients with type 2 diabetes have a higher level of certain chemistry, called anesthetic products (AGEs). In order to provide some AGEs autoflorescence in skin, higher levels of autoflorescence may result in & # 39; The skin is also seen in these patients.
These AGEs can be used with an AGE reader. It is a measuring device the size of a backbone, where the forehead is placed. The light of the AGE reader appears on & # 39; the arm and the skin of the arm reflects the light in another wave of freedom. By measuring the wavelength in wavelength, you can see whether the car's presence of & # 39; the skin has increased. This simple method does not look and takes only ten seconds. The AGE reader was developed by researchers at the UMCG and is sold by Diagnostics.
Researchers are now investigating whether autofluorescence can cause the development of type 2 diabetes, cardiovascular disease and death for people who are not (yet) ill. To this end, they used Lifelines, a data and biobank there were information about the health of 167,000 people. Autofluorescence was also appreciated for most participants with an AGE reader. For this study, the researchers see the data of 72,880 people who do not have cardiovascular disease or diabetes in the first round of research.
In the second round of research, averaging four years later, 1.4% of them have developed diabetes, 1.7% had died of cardiovascular disease and 1.3% (928 people). When the researchers of this now ill or deceased persons were trying on the autofuoriferous measurements of 4 years earlier and compared them with the people who were not ill, the skin's autoflorescence was a great predictive value.
The higher the result of autoflora, the greater the chance to develop type 2 diabetes or cardiovascular disease, and the greater the chance of dying, & # 39; since wolffenbuttel. The prescribed value was independent of various traditional risk factors, such as overweight, metabolic syndrome and increased glucose levels. This means that in people who feel healthy without obesity and other risk factors, autoflorescence is an important example of future illness and death. & # 39;
Low-threshold use of AGE reader
To use the AGE reader easily and can be used by anyone, such as non-medical staff, the low-threshold can be used, whereas the (family) physician can see how risky invoices can be dropped in & # 39; the case of increased auto fluorescence in demand with the prospective patient. became. For example, by stopping smoking, healing of enough experience, it works on a specific weight and treats cholesterol and blood pressure, "says Wolffenbuttel.
The starting point for scientific research at the UMCG is to add more healthy years to life. Therefore, we investigate the mechanisms of disease (which concerns a disease), prevention (disease prevention) and, in the case of illness, to a new, innovative way of determining and treating.
Lifelines is a large-scale research program with the aim of better understanding how people can grow older healthy. The health of 167,000 inhabitants of the Northern Netherlands, spread over 3 generations, is being monitored for a long time. With the collected data, both data and biomaterials can research scientists in the Netherlands and abroad. Lifelines is the largest biobank in the Netherlands. Bruce Wolffenbuttel is one of the founders of Lifelines.