According to a new study, patients who take a hypothyroidism treatment may be at increased risk for atrial fibrillation, a common cardiac rhythm disorder associated with stroke.
The findings were presented by researchers at the Heart Research Center at the Intermountain Medical Center in Salt Lake City at the American Heart Association Science Session in Chicago.
"We know that people with hypothyroidism have a high risk of atrial fibrillation, but they do not consider the risk of being considered a normal range of thyroid hormones. This study shows that we may want to review what we call normal. "Said senior researcher Jeffrey Anderson.
The researchers examined the electronic medical records of 174,914 patients treated at the Intermountain Healthcare facility where free thyroxine (fT4) levels were recorded and without thyroid replacement therapy. The researchers divided the normal range of fT4 into four quartiles and then examined the patient's record for current or future atrial fibrillation diagnosis.
The researchers found that patients with the highest levels of fT4 had a 40% increase in existing atrial fibrillation compared with the lowest patients, and a 16% increase in newly developed atrial fibrillation during 3 years of follow-up.
These results suggest that the optimal healthy range of fT4 should be reviewed and redefined according to Anderson.
"Thyroid hormones require weight loss and more energy and can lead to people being treated at the upper end of the normal range," said Dr. Anderson, "Are we at high risk for people with atrial fibrillation and high risk of stroke?"
This study showed that fT4 should be measured with thyroid stimulating hormone (TSH). Thyroid stimulating hormone (TSH) is more commonly tested in patients with irregular thyroid hormone levels, but not within the normal range of refinement risk .
"The next step for researchers is randomized trials to see if targeting fT4 to lower femoral downlifts in patients receiving thyroid hormone replacement therapy lowers the risk of atrial fibrillation and stroke. "Dr. Anderson said.
Posted: November 11, 2018 at 2:01 pm