Thursday , June 1 2023

Antibiotics Makes Super Bacteria That Can Kill Cancer in 2050 |


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Abuse of antibiotics can create 700,000 people a year in the world by creating Superbugs. This phenomenon is considered an epidemic that has serious consequences. Since 2050, according to the World Health Organization (WHO), Superbug will now kill more than 10 million people annually, exceeding the number of cancer deaths (8.2 million).

In addition to the risk to the population, this is a major challenge for the industry as the bacteria become more resistant than ever before, and the drug quickly becomes obsolete and is not interested in the pharmaceutical industry.

To reverse this scenario, it is important for the patient to stop medication and be more discerning when the doctor prescribes this type of medication. But not only that. Farms and livestock also have uncontrolled use of antibiotics and the wrong disposal of residual medicines.

The first antibiotic created in 1928 by Alexander Fleming, a British pharmacologist, is penicillin. Black fever, tuberculosis, epidemics, and typhoid.

"The emergence of antibiotics, vaccines and basic hygiene has extended the average life expectancy of humans within 30 years," says Maria Lavínea Figueiredo, Pfizer's anti-infective product manager.

But Fleming himself rejected his invention in the late 1930s and warned the medical community about mutations that bacteria are experiencing. Over the years, his fear of using indiscriminate medication has been confirmed.

Doctors have not always prescribed cures properly, but many patients do not respect prescribed doses, and use the leftovers themselves to eat or play in the environment.

"Do not exclude antibiotics from sinks, trash cans or toilets," says Flávia Rossi, Director of Microbiology Services at Sao Paulo Hospital. In contact with soil, river and sea bacterium, these residues prefer the appearance of resistant microorganisms. "It is advisable to provide what remains in the pharmacy providing the collection program."

Flávia, an infectologist at the WHO Microbial Surveillance Group, has followed recent studies proven by super bats about the pollution of water in Guarabara Bay, Rio de Janeiro. However, the most resistant areas flourish in hospitals.

Last year, the State Health Department of São Paulo identified 5,067 resistant microorganisms in 343 health units and was almost always identified in the Adult Intensive Care Unit (ICU).

Mario Bitcole / UOL

In the hospital environment,

In Brazil, carbapenens bacteria are the most afraid of authorities. Three types of it are rarely treated with antibiotics. The most frightening thing is Acinetobacter. "When identified in Brazil, the likelihood of pharmacological failure is 60% to 80%," says Flávia Rossi.

As a result, the patient spent more time at the hospital, hospital costs skyrocketed, and mortality increased.

Livestock antibiotic

Many bacteria are resistant to antibiotics in the food chain. 70% of drug use occurs in agriculture-related industries. Fungicides are used on farms. In animals, antibiotics prevent disease and increase the amount of livestock.

"It's usable, but it's under control, and it's widely used today," says an infection scientist. "If you eat badly cooked meat, you can reach people and resist bacteria in the field."

October, George Washington University Research Group, United When using antibiotics to create birds, a super bug emerged that reached the man.. The disbelief that has persisted since the 1970s has come to an end when scientists for the first time have taken over new organs and discovered bacteria that only adapted to human organisms.

No remedy

Another super-goiteria that plagues the country is KPC, and it has not been cured yet and is still untreated. In the United States, remedies are available for three years.

Pfizer expects the Torgena drug to be released by Brazil's Anvisa (National Sanitary Surveillance), which is expected to take 8-12 years from the time it is developed to antibiotics. When you arrive [o remédio]Bacteria already have tolerance. "Says Eurico Correa, the medical director of the lab.

Microorganisms cause pneumonia, urinary tract infection and blood flow. The symptoms range from tachycardia, fever and bloating to multiple organ failure.

Rapid adaptation of the bacteria makes the development of antibiotics a profitable business for pharmaceuticals. In July, Norvatis, another industry giant, It has definitely terminated its antibacterial studies such as other pharmaceutical companies such as AstraZeneca, Sanofi, Allergan, Medicines..

"The market has broken down." We are now at a much faster pace than our ability to supply new antibiotics, "said David Shlaes, market consultant and chief executive officer at the time.

Consumer participation

Faced with delicate scenarios, the industry wants to involve patients in a fight against super insects. Industry experts want to popularize the answers to these questions:

1 – I feel good already, can I stop antibiotics? no. Drug administration should be strictly followed by prescription, taking into account the number of days and intervals between doses.

2 – Can I mix antibiotics with alcohol? no. The diuretic action of alcohol can not only overload the liver, but also reduce the drug concentration in the blood.

3 – I have a flu. Does antibiotics resolve? The side effect is a virus that does not respond to antibiotics. Therefore, do not take any medication that is out of the previous prescription.

4 – Is the hospital a dangerous place? If you really have to go, be warned! Minimize hospital visits, wash hands with soap and water, and use alcohol gels. Never touch probes, serum, or catheters, and never sit on hospital beds.

5 – Can I split the tablet in half? Not at all. Very low doses can promote adaptation rather than clearing microorganisms. If you have difficulty swallowing a pill, ask your doctor for a liquid alternative.

An HC-infected scholar warned that "we live in a silent bacterial epidemic." "Silence until it appears, and if that happens, there is no treatment option.

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