Tuesday , May 30 2023

Health | The appendix plays an important role in the onset of Parkinson's disease.


What if Parkinson's disease does not develop only in the brain? A disease designated as a neurodegenerative disease can be one of its origins in the digestive system. A study of 1.5 million people in Sweden published in Science Translational Medicine reveals the link between appendicitis and Parkinson's outbreak.

The study, conducted by a 1.7 million people survey, found that patients who removed the cecum were 20 percent less likely to develop Parkinson's disease. On the other hand, people who have undergone appendectomy and whose onset is delayed by an average of 4 years.

In addition, previous protein deposits associated with this disease were found in the appendix and other parts of the digestive system, adding existing evidence linking the intestinal tract to brain disease.

The appendix is ​​useless.

The appendix contains alpha-synuclein proteins known to accumulate in the brain of patients with Parkinson's disease. "Alpha-synuclein is a protein that does not like to move but can move from neurons to neurons. When you enter the brain, it germinates and spreads, causing neurotoxicity, eventually leading to Parkinson's disease", Explains Viviane Labrie, one of the authors of the study.

Although its reputation is largely unnecessary, the Appendix actually plays an important role in our immune system, which regulates the composition of our intestinal bacteria. As shown in our study, Parkinson's disease,

Careful, this study does not recommend that you do not keep the appendix away. "It does not mean that if you have resected, you will not get Parkinson's."Warn the researcher. The causal relationship is not established at present. As in this type of study, other factors that are not considered can explain the difference between temperate and other people.

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