RNA in the fight against multiple sclerosis
RNA vaccines protect against the infectious disease Covid-19. Now, Mainz-based company Biontech is showing that such an active ingredient may also help fight multiple sclerosis (MS). Biontech is currently working on an anti-inflammatory vaccine. And that gives hope.
Positive effects in animal experiments
Multiple sclerosis is an autoimmune disease with various forms in which chronic inflammation develops in the central nervous system and leads to severe limitations. The disease is hitherto incurable. In one study, Biontech researchers significantly improved the symptoms of an MS-like disease in mice or prevented the outbreak. This is reported by the scientific journal Science.
Effectiveness also in humans?
An independent expert speaks of very exciting data, but calls for caution. “You never know whether it will work so well in humans,” said Ralf Gold, chairman of the medical advisory board of the German Multiple Sclerosis Society (DMSG), of the Berliner Zeitung.
Biontech founder Uğur Şahin told the German press office that the compatibility of this approach is currently being tested and that preparations are being made to be investigated in humans. Clinical trials can begin in two to three years “if everything goes according to plan”. In addition, researchers want to investigate RNA vaccinations for other applications and diseases, including cancer and chronic inflammatory diseases such as arthritis.