TAMPA (AFP) – should you take aspirations of heart disease without concern? The remark is controversial, and the medical advices meant.
However, an overview of scientific data on the subject has shown that each benefit is balanced and balanced by a bleeding risk agreement.
Aspirin is a blood donor and can help prevent symptoms that can lead to heart failure or stroke. But aspirin also stimulates the risk of anemia in the brain, stomach and intestine.
"When considering the totality of evidence, cardiovascular benefits associated with aspirin, modesty and, however, are balanced by major bleeding events," the report by researchers at King's College Hospital in London said. .
It was published on Tuesday (January 22) in & # 39; the evening of & # 39; a US Medical Association (JAMA).
The meta-analysis examined 10 prior studies with a total of more than 164,000 people with an average age of 62.
Multiple aspirin users for those who do not take aspirin have found researchers "significant reductions" in cardiovascular disease locks, heart attacks and death among those who took aspirin.
Aspirin use is also associated with an increased risk of "major bleeding events in comparison to no aspirin," it said.
Statistically, the advantages were close to the risk.
If 10,000 people without heart disease had any aspirin names for a year, 61 of them would have a heart attack or stick, Kevin McConway, emeritus professor of appropriate statistics, explained at The Open University.
If 10,000 comparable people have taken aspirin for a year, 57 of them have a heart attack or stick.
"Only four less in 10,000, but that still has some importance on how common the type of disease is and how serious cardiovascular disease is," McConway said, "it was not involved in a study."
Heart disease is the world's top man, who lives 17.9 million every year to bring the planet, one third of all dead, says the World Health Organization.
"The downfall is the increase of major bleeding events, including bleeding in the heels and brain or large blood in either the stomach or the good," adds McConway.
In a non-aspirin feeding pool of 10,000 people, 16 would have had one event in a year, compared to 23 among aspirin workers.
In other words, so-called seven more large bloods annually, they described McConway as a "substantial increase", even though the annual risk of anemia is "still not high".
According to a recent national study of American adults, about half reported regular aspirin use.
Sean Zheng, a cardiologist at King's College Hospital in London and lead author of the JAMA report, said the public didn't understand that taking low-dose, or baby-aspirin, is important risk.
"In my opinion, there is no place for routine use of aspirin in patients who are healthy", he told AFP.
"Perhaps it's about the controller and considered as baby aspirin, but our data is always showing it's a real risk and you shouldn't expect it to be perfectly safe and secure. . "
Aspirin is not offered in Britain for prevention of heart power.
But in the United States, the Task Force advises & # 39; an American Healthcare Service & # 39; The Beginning of & # 39; a low dose aspirin use for primary prevention of cardiovascular disease (CVD) and colorectal cancer in adults in & # 39; e 50 to 59 years of age, at a 10 percent or greater 10 year CVD risk, are not at increased risk for blood, a life of at least 10 years ".
According to Jeremy Pearson, medical director of the British Heart Foundation, the meta-analysis is "valuable updates to our knowledge, but does not change the current perspective".
"It confirms that the average risk of damage is greater so that guidelines should not be changed."
CANCER BENEFITS & # 39; NEUTRAL & # 39;
The study is also in the prefective benefits of aspirin decline when it comes to cancer and found "no overall association between aspirin use and cancer or cancer mortality".
The review pointed to one study that found a 15-day reduction in cancer day that followed in connection with aspirin use after fifty years.
However, the same findings were not replicated in a second problem, which followed approximately 500 patients for seven years.
"The findings of this study suggest that the association of aspirin with cancer results is neutral, with no advice of harm or benefit from the available current evidence", says the JAMA report.